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编 号：F665335
分子式：C25H26N4
分子量：382.5
分子式：C25H26N4
分子量：382.5
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CAS No: 115618-99-0
产品详情
生物活性：
Quinoprazine is a potent inhibitor of Vaccinia virus DNA synthesis with an IC50 value of 10 μM. Quinoprazine has antimalarial activity against Plasmodium berghei and also displays antiprion potency, significantly decreases PrPSc levels-.
体内研究：
Quinoprazine is a 1-alkyl-4-[4-(heterylamino)phenyl]piperazines derivate, Quinoprazine (0.25 g/kg; i.p.; single dose) suppresses the growth of larvocysts of Echinococcus multilocularis in cotton rats.Quinoprazine (0.2-0.5 g/kg; p.o.; single dose) acts against the adult Hymenolepis nana. Exptl. and cures infected mice radically.
体外研究：
Quinoprazine shows antimalarial action against Plasmodium berghei, the chloroquine-resistant isolate LN-K65.Quinoprazine blocks Vaccinia Virus infection by inhibiting DNA synthesis.Quinoprazine (IND2118) displays good antiprion potency and inhibits baseline PrPSc with reducing rates of 76% (dividing cells) and 51% (nondividing cells), respectively. Reducing PrPSc levels by >30% is considered to have good antiprion potency. Quinoprazine (IND2118) shows low cytotoxicity with reducing rates of 25% (dividing cells) and 24% (nondividing cells), respectively. Reducing cells Quinoprazine 相关抗体:
Quinoprazine is a potent inhibitor of Vaccinia virus DNA synthesis with an IC50 value of 10 μM. Quinoprazine has antimalarial activity against Plasmodium berghei and also displays antiprion potency, significantly decreases PrPSc levels-.
体内研究：
Quinoprazine is a 1-alkyl-4-[4-(heterylamino)phenyl]piperazines derivate, Quinoprazine (0.25 g/kg; i.p.; single dose) suppresses the growth of larvocysts of Echinococcus multilocularis in cotton rats.Quinoprazine (0.2-0.5 g/kg; p.o.; single dose) acts against the adult Hymenolepis nana. Exptl. and cures infected mice radically.
体外研究：
Quinoprazine shows antimalarial action against Plasmodium berghei, the chloroquine-resistant isolate LN-K65.Quinoprazine blocks Vaccinia Virus infection by inhibiting DNA synthesis.Quinoprazine (IND2118) displays good antiprion potency and inhibits baseline PrPSc with reducing rates of 76% (dividing cells) and 51% (nondividing cells), respectively. Reducing PrPSc levels by >30% is considered to have good antiprion potency. Quinoprazine (IND2118) shows low cytotoxicity with reducing rates of 25% (dividing cells) and 24% (nondividing cells), respectively. Reducing cells Quinoprazine 相关抗体:
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