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编 号:F664784
分子式:C17H13ClN2O2
分子量:312.75
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生物活性:
DHODH-IN-3 (compound 3) is a potent inhibitor of Human Dihydroorotate Dehydrogenases?(HsDHODH) with an IC50 value of 261 nM. DHODH-IN-3 binds to the the ubiquinone binding cavities in DHODH with a Kiapp of 32 nM. DHODH-IN-3 has the potential for malaria treatment.

体外研究:
DHODH-IN-3 (compound 3) show good inhibitory effects onHsDHODH with IC50 value of 261 nM. It binds to HsDHODH with a Kiapp value of 32 nM.
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