产品
编 号:F664276
分子式:C13H9F4NO2S
分子量:319.27
产品类型
结构图
CAS No: 1141768-04-8
联系客服
产品详情
生物活性:
PVZB1194 is a biphenyl-type inhibitor of Kinesin spindle protein Eg5 or KIF11. Eg5 is related to the cell cycle, and Eg5 inhibition can lead to cell cycle arrest and apoptosis. PVZB1194 exhibits anticancer potential via inhibiting Eg5 ATPase activity. PVZB1194 binds to the α4/α6 allosteric pocket, and shows ATP competetive activity.