产品
编 号：F652763
分子式：C20H22N2O2
分子量：322.4
分子式：C20H22N2O2
分子量：322.4
产品类型
规格
价格
是否有货
5mg
560
In-stock
10mg
960
In-stock
25mg
2000
In-stock
50mg
3600
In-stock
100mg
6000
In-stock
结构图
CAS No: 100823-03-8
产品详情
生物活性：
TC11 is a MCL1 degrader. TC11 is also a Caspase-9 and CDK1 activator. TC11 structurally relates to immunomodulatory agents as phenylphthalimide derivative. TC11 induces apoptotic death caused by degradation of MCL1 during prolonged mitotic arrest.
体外研究：
TC11 (0~30 μM; 24 hours; KMS34 cells) induces cell death in KMS34.TC11 (5 μM; 0~48 hours; KMS34 cells) induces cell death occurs through an apoptotic pathway and downregulates MCL1 expression.TC11 (5 μM; 24 hours; KMS34 cells) induces M arrest.
TC11 is a MCL1 degrader. TC11 is also a Caspase-9 and CDK1 activator. TC11 structurally relates to immunomodulatory agents as phenylphthalimide derivative. TC11 induces apoptotic death caused by degradation of MCL1 during prolonged mitotic arrest.
体外研究：
TC11 (0~30 μM; 24 hours; KMS34 cells) induces cell death in KMS34.TC11 (5 μM; 0~48 hours; KMS34 cells) induces cell death occurs through an apoptotic pathway and downregulates MCL1 expression.TC11 (5 μM; 24 hours; KMS34 cells) induces M arrest.
产品资料
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