产品
编 号：F649216
分子式：C19H10ClF4N5O3S2
分子量：531.89
分子式：C19H10ClF4N5O3S2
分子量：531.89
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 1235406-03-7
产品详情
生物活性：
PF-05186462 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channel, with an IC50 of 21 nM. PF-05186462 shows significant selectivity for Nav1.7 versus other sodium channels (Nav 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, and 1.8). PF-05186462 can be used for the research of acute or chronic pain.
体外研究：
PF-05186462 inhibits human Nav1.7 channels (IC50=21 nM) in HEK293 cells.PF-05186462 exhibits a high plasma protein binding rate.
PF-05186462 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channel, with an IC50 of 21 nM. PF-05186462 shows significant selectivity for Nav1.7 versus other sodium channels (Nav 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, and 1.8). PF-05186462 can be used for the research of acute or chronic pain.
体外研究：
PF-05186462 inhibits human Nav1.7 channels (IC50=21 nM) in HEK293 cells.PF-05186462 exhibits a high plasma protein binding rate.
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