产品
编 号：F643561
分子式：C15H20N4O3
分子量：304.34
分子式：C15H20N4O3
分子量：304.34
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 1630760-60-9
产品详情
生物活性：
(R)-DNMDP is a potent and selective cancer cell cytotoxic agent. (R)-DNMDP, the R-form of DNMDP, binds PDE3A directly. (R)-DNMDP has a 500-fold lower EC50 compared to the (S)-enantiomer in HeLa cell line.
体外研究：
(R)-DNMDP (0.1 pM-1 mM; for 48 hours) has a 500-fold lower EC50 compared to the (S)-enantiomer in HeLa cell line.(S)-DNMDP has non-cytotoxic. Binding of PDE3A to the linker analogue is blocked by both trequinsin and (R)-DNMDP, but not by the (S)-DNMDP.
(R)-DNMDP is a potent and selective cancer cell cytotoxic agent. (R)-DNMDP, the R-form of DNMDP, binds PDE3A directly. (R)-DNMDP has a 500-fold lower EC50 compared to the (S)-enantiomer in HeLa cell line.
体外研究：
(R)-DNMDP (0.1 pM-1 mM; for 48 hours) has a 500-fold lower EC50 compared to the (S)-enantiomer in HeLa cell line.(S)-DNMDP has non-cytotoxic. Binding of PDE3A to the linker analogue is blocked by both trequinsin and (R)-DNMDP, but not by the (S)-DNMDP.
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