产品
编 号:F642194
分子式:C37H39ClN4O4
分子量:639.18
产品类型
结构图
CAS No: 1810769-31-3
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产品详情
生物活性:
Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.
体内研究:
Mcl1-IN-9 inhibits the growth of hematological and triple negative breast cancer xenografts at well tolerated doses.
体外研究:
Mcl1-IN-9 inhibits growth of Mcl-1 dependent tumor cell lines in the nanomolar range.