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编 号:F641672
分子式:C129H217N29O39
分子量:2798.32
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生物活性:
st-Ht31 is a membrane-permeable peptide inhibitor of protein kinase A (PKA) anchoring. st-Ht31 induces robust cholesterol/phospholipid efflux. st-Ht31 completely reverses foam cell formation and restores the metabolic health of macrophage.

体外研究:
st-Ht31 (5 μM; 2 h) enhances cholesterol/phospholipid efflux in BHK cells and RAW macrophages.st-Ht31 (10μM; 24 h) reverses foam cell formation and restores metabolic health of macrophage.st-Ht31 (20 μM; 20 min) abolishes the cAMP inhibition of PMA-induced ERK1/2 activation n HEK293T cells.
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