产品
编 号：F641110
分子式：C48H47N4O10P
分子量：870.88
分子式：C48H47N4O10P
分子量：870.88
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 1967815-98-0
产品详情
生物活性：
D-3, a phosphorpeptide, is an efficient, simple, and specific iPSC-eliminating agent.
体外研究：
D-3 prevents residual iPSC-induced teratoma formation in a mouse tumorigenicity assay.D-3 induces obvious loss of viability in 201B7 cells, with half maximal inhibitory concentration value of 192.3 ± 57.4 μM.D-3 induces an increase in the amount of activated elF2a, p38, and p44/42 MAPK, whichare activated in response to cellular stress. D-3 also increases the number of Annexin-V and SYTOX-positive cells, indicating apoptotic and dead cells after D-3 treatment.D-3 has little influence on various non-iPSCs, including hepatocytes and neurons.
D-3, a phosphorpeptide, is an efficient, simple, and specific iPSC-eliminating agent.
体外研究：
D-3 prevents residual iPSC-induced teratoma formation in a mouse tumorigenicity assay.D-3 induces obvious loss of viability in 201B7 cells, with half maximal inhibitory concentration value of 192.3 ± 57.4 μM.D-3 induces an increase in the amount of activated elF2a, p38, and p44/42 MAPK, whichare activated in response to cellular stress. D-3 also increases the number of Annexin-V and SYTOX-positive cells, indicating apoptotic and dead cells after D-3 treatment.D-3 has little influence on various non-iPSCs, including hepatocytes and neurons.
产品资料
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