产品
编 号：F067511
分子式：C5H3N4NaO3
分子量：190.09
分子式：C5H3N4NaO3
分子量：190.09
产品类型
规格
价格
是否有货
200mg
400
In-stock
结构图
CAS No: 1198-77-2
产品详情
生物活性：
Uric acid sodium (Monosodium urate), scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid sodium can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation.
体内研究：
uric acid sodium (250 mg/kg；口服) 可改善吲哚美辛诱导的肠病。口服 uric acid sodium 可减少吲哚美辛小鼠模型中回肠中 ROS 的积累-诱发性肠病。Animal Model:Eight-week-old male C57BL/6J mice
Dosage:250 mg/kg body weight
Administration:P.o.
Result:When mice treated with indomethacin were concurrently administered uric acid orally, ulcer areas were significantly reduced, in a uric acid dose-dependent manner.
体外研究：
Uric acid sodium (400 μM；48 小时) 钠可保护 Caco-2 细胞免受吲哚美辛诱导的脂质过氧化。 用吲哚美辛和尿酸共同处理细胞 (200 μM IND加 400 μM UA；24 小时) 钠与仅用吲哚美辛孵育的细胞相比显著降低 ROS 水平。用吲哚美辛和 Uric acid sodium (200 μM IND 加 400 μM UA；24 小时) 钠处理的 Caco-2 细胞的细胞活力高于仅用吲哚美辛处理的细胞。尿酸钠通过其抗氧化活性对吲哚美辛引起的肠细胞变化具有保护作用。
Uric acid sodium (Monosodium urate), scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid sodium can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation.
体内研究：
uric acid sodium (250 mg/kg；口服) 可改善吲哚美辛诱导的肠病。口服 uric acid sodium 可减少吲哚美辛小鼠模型中回肠中 ROS 的积累-诱发性肠病。Animal Model:Eight-week-old male C57BL/6J mice
Dosage:250 mg/kg body weight
Administration:P.o.
Result:When mice treated with indomethacin were concurrently administered uric acid orally, ulcer areas were significantly reduced, in a uric acid dose-dependent manner.
体外研究：
Uric acid sodium (400 μM；48 小时) 钠可保护 Caco-2 细胞免受吲哚美辛诱导的脂质过氧化。 用吲哚美辛和尿酸共同处理细胞 (200 μM IND加 400 μM UA；24 小时) 钠与仅用吲哚美辛孵育的细胞相比显著降低 ROS 水平。用吲哚美辛和 Uric acid sodium (200 μM IND 加 400 μM UA；24 小时) 钠处理的 Caco-2 细胞的细胞活力高于仅用吲哚美辛处理的细胞。尿酸钠通过其抗氧化活性对吲哚美辛引起的肠细胞变化具有保护作用。
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