产品
编 号:F628277
分子式:C20H17ClN3O3P
分子量:413.79
产品类型
结构图
CAS No: 1018450-26-4
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产品详情
生物活性:
Fosdevirine (GSK2248761) is is a potent, selective, non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1) replication with low nanomolar activity in vitro. Fosdevirine shows good activity against a broad range of HIV-1 strains, including efavirenz (HY-10572)-resistant clinical isolates.
体外研究:
Fosdevirine 对 K103N 和 Y181C 单点突变表现出强大的体外抗病毒功效,对大多数双突变体也同样有效。