产品
编 号：F627778
分子式：C17H22N4
分子量：282.38
分子式：C17H22N4
分子量：282.38
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规格
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CAS No: 1065110-43-1
产品详情
生物活性：
PF-4479745 is a potent and selective 5-HT2C receptor agonist (EC50: 10 nM, ki: 15 nM). PF-4479745 can be used in the research of cardiovascular disease like hypertension.
体内研究：
PF-4479745 (compound 17, intravenous injection) shows high clearance rate (104 mL/min/kg).PF-4479745 demonstrates a robust dose-dependent effect in canine PUP (peak urethral pressure) model of SUI (stress urinary incontinence).
体外研究：
PF-4479745 (copmpound 17) exhibits metabolic stability in both human liver microsomes (HLM) and human hepatocytes.
PF-4479745 is a potent and selective 5-HT2C receptor agonist (EC50: 10 nM, ki: 15 nM). PF-4479745 can be used in the research of cardiovascular disease like hypertension.
体内研究：
PF-4479745 (compound 17, intravenous injection) shows high clearance rate (104 mL/min/kg).PF-4479745 demonstrates a robust dose-dependent effect in canine PUP (peak urethral pressure) model of SUI (stress urinary incontinence).
体外研究：
PF-4479745 (copmpound 17) exhibits metabolic stability in both human liver microsomes (HLM) and human hepatocytes.
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