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编 号:F626415
分子式:C23H26N4O4
分子量:422.48
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生物活性:
(R)-8-Azido-2-(Fmoc-amino)octanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (R)-8-Azido-2-(Fmoc-amino)octanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

体外研究:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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