产品
编 号：F626412
分子式：C15H14Cl2N4O
分子量：337.2
分子式：C15H14Cl2N4O
分子量：337.2
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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结构图
CAS No: 1191908-14-1
产品详情
生物活性：
ADRA1D receptor antagonist 1 is a potent, selective and orally active α1D adrenoceptor antagonist, with a Ki of 1.6 nM.
体内研究：
ADRA1D receptor antagonist 1 (4.4 μg/kg; i.v.) dose-dependently decreases the non-voiding bladder contractions during the urinary storage phase in rats with BOO.Animal Model:Rat with bladder outlet obstruction (BOO)
Dosage:4.4 μg/kg
Administration:Intravenous injection
Result:Dose-dependently decreased the non-voiding bladder contractions during urinary storage phase in rats with BOO.
体外研究：
ADRA1D receptor antagonist 1 shows low hERG inhibition.ADRA1D receptor antagonist 1 exhibits higher selectivity for α1D-AR over α1A- and α1B-ARs .
ADRA1D receptor antagonist 1 is a potent, selective and orally active α1D adrenoceptor antagonist, with a Ki of 1.6 nM.
体内研究：
ADRA1D receptor antagonist 1 (4.4 μg/kg; i.v.) dose-dependently decreases the non-voiding bladder contractions during the urinary storage phase in rats with BOO.Animal Model:Rat with bladder outlet obstruction (BOO)
Dosage:4.4 μg/kg
Administration:Intravenous injection
Result:Dose-dependently decreased the non-voiding bladder contractions during urinary storage phase in rats with BOO.
体外研究：
ADRA1D receptor antagonist 1 shows low hERG inhibition.ADRA1D receptor antagonist 1 exhibits higher selectivity for α1D-AR over α1A- and α1B-ARs .
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