产品
编 号:F626227
分子式:C16H28ClN3O4
分子量:361.86
产品类型
结构图
CAS No: 1208862-61-6
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产品详情
生物活性:
H-Ile-Pro-Pro-OH hydrochloride, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE) with an IC50 of 5 μM. Antihypertensive tripeptides.
体内研究:
Ile-Pro-Pro (IPP; 30 mg/kg per day; 0.3 g/L) attenuates arterial dysfunction in L-NAME-treated ratsIle-Pro-Pro decreases blood pressure in spontaneously hypertensive rats (SHR) .Ile-Pro-Pro attenuates the development of atherosclerosis in apolipoprotein E-deficient(apoE(-/-)) mice.
体外研究:
Ile-Pro-Pro (IPP; 1 nM, 0.1 μM, and 10 μM) increases nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs).