产品
编 号：F625928
分子式：C4H8O7P2
分子量：230.05
分子式：C4H8O7P2
分子量：230.05
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CAS No: 1226901-43-4
产品详情
生物活性：
BPH-1086 (compound 10) is an IspH inhibitor, IspH domain fused with ribosomal protein S1 (RPS1) can bind to mRNA or form part of the bacterial ribosome.
体外研究：
IspH (LytB) is the last enzyme in the nonmevalonate pathway, IspH domains can be fused to either the ribosomal protein S1 (RPS1), IspH–RPS1 binds to mRNA or forms part of the bacterial ribosome.IspH–RPS1 proteins are present in anaerobes found in the human gut and some, such as Clostridium botulinum, C. tetani and Fusobacterium nucleatum, are pathogens.IspH inhibitor will therefore kill bacteria directly, as with other antibiotics, but will also kill persistent bacteria by microptosis.
BPH-1086 (compound 10) is an IspH inhibitor, IspH domain fused with ribosomal protein S1 (RPS1) can bind to mRNA or form part of the bacterial ribosome.
体外研究：
IspH (LytB) is the last enzyme in the nonmevalonate pathway, IspH domains can be fused to either the ribosomal protein S1 (RPS1), IspH–RPS1 binds to mRNA or forms part of the bacterial ribosome.IspH–RPS1 proteins are present in anaerobes found in the human gut and some, such as Clostridium botulinum, C. tetani and Fusobacterium nucleatum, are pathogens.IspH inhibitor will therefore kill bacteria directly, as with other antibiotics, but will also kill persistent bacteria by microptosis.
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