产品
编 号:F625863
分子式:C20H29ClFN5O2
分子量:425.93
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1mg
3750
In-stock
5mg
11250
In-stock
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生物活性:
AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator. AZD2423 has an IC50 of 1.2 nM for CCR2 Ca2+ flux .

体外研究:
AZD2423 inhibits MCP-1 induced calcium mobilization and chemotaxis of THP-1 cell line with an IC50 of 4 nM.
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