产品
编 号：F625568
分子式：C28H27BrNO3P
分子量：536.4
分子式：C28H27BrNO3P
分子量：536.4
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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25mg
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50mg
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100mg
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结构图
CAS No: 1254044-41-1
产品详情
生物活性：
Mito-apocynin (C2), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP + cation. Mito-apocynin (C2) exhibits antineuroinflammatory effect.
体内研究：
Mito-apocynin (C2) (3 mg/kg; p.o.; daily for 12 days) exhibits antineuroinflammatory effect.Animal Model:MPTP mice model of Parkinson’s Disease
Dosage:3 mg/kg
Administration:Oral gavage; daily for 12 days
Result:Significantly attenuated MPTP-induced glial cell activation, proinflammatory cytokine upregulation, inducible nitric oxide synthase, and NOX2 components (gp91phox).
Mito-apocynin (C2), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP + cation. Mito-apocynin (C2) exhibits antineuroinflammatory effect.
体内研究：
Mito-apocynin (C2) (3 mg/kg; p.o.; daily for 12 days) exhibits antineuroinflammatory effect.Animal Model:MPTP mice model of Parkinson’s Disease
Dosage:3 mg/kg
Administration:Oral gavage; daily for 12 days
Result:Significantly attenuated MPTP-induced glial cell activation, proinflammatory cytokine upregulation, inducible nitric oxide synthase, and NOX2 components (gp91phox).
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