产品
编 号：F624767
分子式：C70H121N29O15S4
分子量：1737.16
分子式：C70H121N29O15S4
分子量：1737.16
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 1313027-43-8
产品详情
生物活性：
MM 54 (compound 5) is a competitive antagonist at APJ, with an IC50 of 93 nM. MM 54 behaves as a potent and selective inhibitor of apelin binding and APLNR activation.
体内研究：
MM 54 (2 mg/kg, ip, bi-weekly for 4 weeks) possesses anti-tumor activity in glioblastoma models with no obvious toxicity.Animal Model:Tumour-bearing nude-mice.
Dosage:2 mg/kg.
Administration:Intraperitoneal injection, bi-weekly for 4 weeks.
Result:Reduced tumor progression (glioblastoma).
体外研究：
MM 54 inhibits more than 95% of apelin binding to APLNR at the dose of 10 μM.
MM 54 (compound 5) is a competitive antagonist at APJ, with an IC50 of 93 nM. MM 54 behaves as a potent and selective inhibitor of apelin binding and APLNR activation.
体内研究：
MM 54 (2 mg/kg, ip, bi-weekly for 4 weeks) possesses anti-tumor activity in glioblastoma models with no obvious toxicity.Animal Model:Tumour-bearing nude-mice.
Dosage:2 mg/kg.
Administration:Intraperitoneal injection, bi-weekly for 4 weeks.
Result:Reduced tumor progression (glioblastoma).
体外研究：
MM 54 inhibits more than 95% of apelin binding to APLNR at the dose of 10 μM.
产品资料
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