产品
编 号：F624300
分子式：C19H26N2O5S2
分子量：426.55
分子式：C19H26N2O5S2
分子量：426.55
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规格
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是否有货
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CAS No: 1356497-91-0
产品详情
生物活性：
ST247 a potent PPARβ/δ inverse agonist. ST247 has a higher affinity to PPARβ/δ. ST247 modulates expression of the activation marker CCL2 in the opposite direction. ST247 efficiently induces the interaction with corepressors. ST247 inhibits the agonist-induced transcriptional activity of PPARβ/δ.
体外研究：
ST247 induces a clearly enhanced interaction of the PPARβ/δ LBD with the SMRT-ID2 peptide, with an EC50 of 10 nM.ST247 down-regulates basal level expression of the peroxisome proliferator responsive element-driven PPARβ/δ target gene ANGPTL4, with an IC50 of 19.1 nM.
ST247 a potent PPARβ/δ inverse agonist. ST247 has a higher affinity to PPARβ/δ. ST247 modulates expression of the activation marker CCL2 in the opposite direction. ST247 efficiently induces the interaction with corepressors. ST247 inhibits the agonist-induced transcriptional activity of PPARβ/δ.
体外研究：
ST247 induces a clearly enhanced interaction of the PPARβ/δ LBD with the SMRT-ID2 peptide, with an EC50 of 10 nM.ST247 down-regulates basal level expression of the peroxisome proliferator responsive element-driven PPARβ/δ target gene ANGPTL4, with an IC50 of 19.1 nM.
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