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编 号:F624274
分子式:C19H20N4O2
分子量:336.39
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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生物活性:
Vafidemstat (ORY-2001) is an oral, brain penetrant, dual lysine-specific histone demethylase (LSD1)/MAO-B inhibitor.

体外研究:
Vafidemstat (ORY-2001), a dual LSD1/MAO-B inhibitor, is a novel epigenetic agent for the treatment of neurodegenerative diseases. LSD1 is a protein that participates in transcription regulation complexes; its modulation can be used to tweak transcriptional imbalances in neurodegenerative disease and redress neuroinflammation and cognitive deficit. Vafidemstat (ORY-2001) can be used in the treatment of Alzheimer's disease.
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