产品
编 号:F623984
分子式:C10H21N5O5
分子量:291.3
产品类型
结构图
CAS No: 1379761-16-6
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产品详情
生物活性:
Aminoxyacetamide-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminoxyacetamide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
体外研究:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.