产品
编 号：F623911
分子式：C26H24FN3O3
分子量：445.49
分子式：C26H24FN3O3
分子量：445.49
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
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5mg
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10mg
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结构图
CAS No: 1382722-47-5
产品详情
生物活性：
MMPI-1154 is a promising novel cardio-cytoprotective imidazole-carboxylic acid (ICA) MMP-2 inhibitor(IC50=6.6 μM) and can be used for the study of acute myocardial infarction. MMPI-1154 also inhibits the activity of MMP-13, MMP-1 and MMP-9 with IC50s of 1.8 μM,10 μM, and 13 μM, respectively.
体外研究：
MMPI-1154 (1-100 μM) inhibits MMP-2 enzyme isolated from rat heart?in vitro, and 100% inhibition appears at the concentraction 100 μM.MMPI-1154 (1 μM) shows significant cardio-cytoprotecion, significantly decreases infarct size in an ex vivo model for acute myocardial infarction.
MMPI-1154 is a promising novel cardio-cytoprotective imidazole-carboxylic acid (ICA) MMP-2 inhibitor(IC50=6.6 μM) and can be used for the study of acute myocardial infarction. MMPI-1154 also inhibits the activity of MMP-13, MMP-1 and MMP-9 with IC50s of 1.8 μM,10 μM, and 13 μM, respectively.
体外研究：
MMPI-1154 (1-100 μM) inhibits MMP-2 enzyme isolated from rat heart?in vitro, and 100% inhibition appears at the concentraction 100 μM.MMPI-1154 (1 μM) shows significant cardio-cytoprotecion, significantly decreases infarct size in an ex vivo model for acute myocardial infarction.
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