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编 号:F623707
分子式:C21H18ClFN4O3
分子量:428.84
产品类型
结构图
CAS No: 1402086-20-7
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生物活性:
Afatinib impurity 11 is an impurity of Afatinib. Afatinib is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively.