产品
编 号：F623287
分子式：C18H18N2O4
分子量：326.35
分子式：C18H18N2O4
分子量：326.35
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 1430798-22-3
产品详情
生物活性：
Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1). Isobutyl-deoxynyboquinone can be used for the research of anticancer.
体内研究：
Isobutyl-deoxynyboquinone (0.5~2 mg/kg; i.v.; 20 hours) achieves average peak plasma concentration levels. Isobutyl-deoxynyboquinone (1 mg/kg; p.o.; 4 hours) achieves peak plasma concentrations.Animal Model:Cats
Dosage:0.5~2 mg/kg (Pharmacokinetic Analysis)
Administration:I.v.
Result:Achieved average peak plasma concentration levels.
Animal Model:Cats
Dosage:1 mg/kg (Pharmacokinetic Analysis)
Administration:P.o.
Result:Achieved peak plasma concentration.
体外研究：
Isobutyl-deoxynyboquinone (0.01~100 μM; OSCC cells) demonstrates greater cytotoxic potency against SCCF1 and SCCF2 cell lines, and less against the SCCF3 cell line. Isobutyl-deoxynyboquinone (0.1~3 μM; 60 minutes; SCCF1 cells) induces cytotoxicity in a dose-dependent manner.
Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1). Isobutyl-deoxynyboquinone can be used for the research of anticancer.
体内研究：
Isobutyl-deoxynyboquinone (0.5~2 mg/kg; i.v.; 20 hours) achieves average peak plasma concentration levels. Isobutyl-deoxynyboquinone (1 mg/kg; p.o.; 4 hours) achieves peak plasma concentrations.Animal Model:Cats
Dosage:0.5~2 mg/kg (Pharmacokinetic Analysis)
Administration:I.v.
Result:Achieved average peak plasma concentration levels.
Animal Model:Cats
Dosage:1 mg/kg (Pharmacokinetic Analysis)
Administration:P.o.
Result:Achieved peak plasma concentration.
体外研究：
Isobutyl-deoxynyboquinone (0.01~100 μM; OSCC cells) demonstrates greater cytotoxic potency against SCCF1 and SCCF2 cell lines, and less against the SCCF3 cell line. Isobutyl-deoxynyboquinone (0.1~3 μM; 60 minutes; SCCF1 cells) induces cytotoxicity in a dose-dependent manner.
产品资料
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