产品
编 号：F623227
分子式：C43H62F3N9O9S2
分子量：970.13
分子式：C43H62F3N9O9S2
分子量：970.13
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 1435781-74-0
产品详情
生物活性：
WKYMVM-NH2 TFA is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist, also activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and activation of the NADPH oxidase.
体内研究：
WKYMVM-NH2 TFA (8?mg/kg; six times; for 5 days) ameliorates DSS-induced ulcerative colitis.WKYMVM-NH2 TFA affects cytokine (IL-17, IFN-γ, IL-6, IL-1β and TNF-α) profiles in the DSS colitis model.Animal Model:Six-week-old C57BL/6 mice, DSS model
Dosage:8?mg/kg
Administration:Subcutaneously injected, six subcutaneous administrations at 12-h intervals, for 5 days
Result:Attenuated the DSS-induced increase in the bleeding score and the stool score.
体外研究：
WKYMVM-NH2 TFA (10-1000?nM; 24?hours) induces Caco-2 cells proliferation.
WKYMVM-NH2 TFA is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist, also activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and activation of the NADPH oxidase.
体内研究：
WKYMVM-NH2 TFA (8?mg/kg; six times; for 5 days) ameliorates DSS-induced ulcerative colitis.WKYMVM-NH2 TFA affects cytokine (IL-17, IFN-γ, IL-6, IL-1β and TNF-α) profiles in the DSS colitis model.Animal Model:Six-week-old C57BL/6 mice, DSS model
Dosage:8?mg/kg
Administration:Subcutaneously injected, six subcutaneous administrations at 12-h intervals, for 5 days
Result:Attenuated the DSS-induced increase in the bleeding score and the stool score.
体外研究：
WKYMVM-NH2 TFA (10-1000?nM; 24?hours) induces Caco-2 cells proliferation.
产品资料
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