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编 号：F623124
分子式：C16H18N8O2S
分子量：386.43
分子式：C16H18N8O2S
分子量：386.43
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CAS No: 1448313-27-6
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生物活性：
Zalunfiban (RUC-4) is a potent, selective platelet αIIbβ3 antagonist (IC50=45 nM). Zalunfiban can be used for the research of myocardial infarction (MI).
体内研究：
Zalunfiban (1~3.86 mg/kg; s.c.; 24 hours) makes platelet aggregationperformed.Zalunfiban (1~3.86 mg/kg; i.m.; 4.5 hours) leads to the onset of high-grade inhibition of platelet aggregation within 15-30 minutes that lasted from ~2 to >4.5 hours in a dose dependent manner.Animal Model:Cynomolgus Monkey
Dosage:1~3.86 mg/kg (Pharmacokinetic Analysis)
Administration:S.c.; 24 hours
Result:Platelet aggregation was performed.
Zalunfiban (RUC-4) is a potent, selective platelet αIIbβ3 antagonist (IC50=45 nM). Zalunfiban can be used for the research of myocardial infarction (MI).
体内研究：
Zalunfiban (1~3.86 mg/kg; s.c.; 24 hours) makes platelet aggregationperformed.Zalunfiban (1~3.86 mg/kg; i.m.; 4.5 hours) leads to the onset of high-grade inhibition of platelet aggregation within 15-30 minutes that lasted from ~2 to >4.5 hours in a dose dependent manner.Animal Model:Cynomolgus Monkey
Dosage:1~3.86 mg/kg (Pharmacokinetic Analysis)
Administration:S.c.; 24 hours
Result:Platelet aggregation was performed.
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