产品
编 号:F622269
分子式:C18H14Cl2N2O2
分子量:361.22
产品类型
结构图
CAS No: 1679333-73-3
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产品详情
生物活性:
MMV008138 is a species-selective IspD (enzyme 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase)-targeting antimalarial agent, with an IC50 of 44 nM for PfIspD (P. falciparum IspD). MMV008138 inhibits the growth of P. falciparum Dd2 strain with an IC50 of 250 nM.
体外研究:
MMV008138 targets the enzyme IspD in the MEP pathway of P. falciparum.MMV008138 does not target human IspD.