产品
编 号:F621519
分子式:C25H19F2N3O3S
分子量:479.5
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
KIN1408 is an agonist of the RIG-1-like receptor (RLR) pathway and exhibits a broad-spectrum antiviral activity. KIN1408 exhibits activity against HCV, influenza A, dengue virus 2, Ebola, Nipah, and Lassa viruses.

体外研究:
KIN1408 has the potency to drive IRF3 activation to induce innate immune gene (MDA5, RIG-1, Mx1, IRF7, and IFIT1 in THP-1 cells) expression and that concomitantly suppress dengue virus2 RNA to levels. KIN1408 also exhibits activity against HCV, influenza A, Ebola, Nipah, and Lassa viruses.
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