产品
编 号：F621482
分子式：C94H174N32O22S2
分子量：2168.72
分子式：C94H174N32O22S2
分子量：2168.72
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CAS No: 1926163-30-5
产品详情
生物活性：
Tumor targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2) is an anti-tumor peptide. Tumor targeted pro-apoptotic peptide disrupts mitochondrial membranes and promotes apoptosis, showing anticancer activity in mice.
体内研究：
Tumor targeted pro-apoptotic peptide inhibits both primary tumor growth and metastasis in mice.Animal Model:Tumor targeted pro-apoptotic peptide (250 μg/mice; tail vein injection; 250 μg a week for 17 weeks) inhibits both primary tumor growth and metastasis in mice.
Dosage:250 μg/mice
Administration:Tail vein injection; 250 μg a week for 17 weeks
Result:Exhibited antitumor activity in vivo.
体外研究：
Tumor targeted pro-apoptotic peptide (10 μM; 0-20 min) induces mitochondrial swelling in DMECs.Tumor targeted pro-apoptotic peptide (100 μM; 72 h) induces apoptosis in DMECs.
Tumor targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2) is an anti-tumor peptide. Tumor targeted pro-apoptotic peptide disrupts mitochondrial membranes and promotes apoptosis, showing anticancer activity in mice.
体内研究：
Tumor targeted pro-apoptotic peptide inhibits both primary tumor growth and metastasis in mice.Animal Model:Tumor targeted pro-apoptotic peptide (250 μg/mice; tail vein injection; 250 μg a week for 17 weeks) inhibits both primary tumor growth and metastasis in mice.
Dosage:250 μg/mice
Administration:Tail vein injection; 250 μg a week for 17 weeks
Result:Exhibited antitumor activity in vivo.
体外研究：
Tumor targeted pro-apoptotic peptide (10 μM; 0-20 min) induces mitochondrial swelling in DMECs.Tumor targeted pro-apoptotic peptide (100 μM; 72 h) induces apoptosis in DMECs.
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