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编 号:F621471
分子式:C31H49FN10O6
分子量:676.78
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生物活性:
Val-Arg-Pro-DL-Arg-Fluoromethylketone is a potent MALT1 inhibitor. Val-Arg-Pro-DL-Arg-Fluoromethylketone inhibits cell proliferation and migration. Val-Arg-Pro-DL-Arg-Fluoromethylketone shows anticancer activity.

体内研究:
Val-Arg-Pro-DL-Arg-Fluoromethylketone (37.5 M*0.2 mL;每隔一天,持续 12 天) 抑制小鼠肿瘤的生长。Animal Model:4-6 weeks, 16-20 g, Female BALB/c nude mice (OCI-LY10 cells)
Dosage:37.5 M*0.2 mL
Administration:Every other day for 12 days
Result:Inhibited the growth of the xenografts and decreased the expression of P65.

体外研究:
Val-Arg-Pro-DL-Arg-Fluoromethylketone (75 mol/L; 6, 12, 24, 36, and 48 h) 抑制 OCI-LY10 细胞的增殖和迁移。
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