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编 号:F621318
分子式:C21H30Cl2N6O4
分子量:501.41
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生物活性:
Xanthine amine congener dihydrochloride (XAC dihydrochloride) is a potent Adenosine A1 receptor and A2?receptor antagonist with IC50 values of 1.8 and 114 nM, respectively. Xanthine amine congener acts as a convulsant agent in mice model.

体内研究:
Xanthine amine congener dihydrochloride is more potent as a convulsant than either caffeine or theophyllin in infusion studies at the dosage 39.8 mg/kg. XAC has no effects by administering the drug via an i.p. injection, the seizure threshold >1000 mg/kg.Animal Model:Mice
Dosage:39.8 mg/kg
Administration:Infusion injection; single dose
Result:Acted as a convulsant agent than either caffeine or theophyllin.
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