产品
编 号：F621174
分子式：C118H178N36O28S
分子量：2580.97
分子式：C118H178N36O28S
分子量：2580.97
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2022956-48-3
产品详情
生物活性：
MOG peptide (35-55) is a fragment 35-55 of myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide. MOG peptide (35-55) is specific to expanded CD4+ T?cells, and induces experimental autoimmune encephalomyelitis (EAE) in animal model.
体内研究：
MOG peptide (35-55) (3 mg/mL for 0.1 mL; s.c.; single dose) results active induction of experimental autoimmune encephalomyelitis (EAE) in mice.MOG peptide (35-55) (200 μg; s.c.; single dose) induces a increasing concentration of the eosinophil chemoattractant eotaxin-1 in the spinal cord in the course of EAE induced in C57BL/6 mice.Animal Model:129S1/SvImJ, C57BL/6 and C57BL/6 X SJL hybrid
Dosage:3 mg/mL, 0.1 mL per mice; accompanied with CFA and 4 mg/mL Mycobacterium tuberculosis
Administration:Subcutaneous injection; single dose
Result:Showed the expected signs of experimental autoimmune encephalomyelitis (EAE), which started with tail loss of tonus and continued in an ascending fashion in mice immunized with MOG35-55.
Animal Model:C57BL/6 mice (8-12 weeks)
Dosage:200 μg
Administration:Subcutaneous injection; single dose; analyzed at pre-onset (day 7 post immunization), onset (day 9-13 post immunization) and peak (day 17-19 post immunization)
Result:Increased eosinophil abundance in the spinal cord increases in the course of EAE.
体外研究：
The expanded CD4+ T?cells are largely specific for the myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide 35-55 (MOG35-55), while clonally expanded CD8+ T?cells were non-responsive to myelin peptides or proteins.
MOG peptide (35-55) is a fragment 35-55 of myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide. MOG peptide (35-55) is specific to expanded CD4+ T?cells, and induces experimental autoimmune encephalomyelitis (EAE) in animal model.
体内研究：
MOG peptide (35-55) (3 mg/mL for 0.1 mL; s.c.; single dose) results active induction of experimental autoimmune encephalomyelitis (EAE) in mice.MOG peptide (35-55) (200 μg; s.c.; single dose) induces a increasing concentration of the eosinophil chemoattractant eotaxin-1 in the spinal cord in the course of EAE induced in C57BL/6 mice.Animal Model:129S1/SvImJ, C57BL/6 and C57BL/6 X SJL hybrid
Dosage:3 mg/mL, 0.1 mL per mice; accompanied with CFA and 4 mg/mL Mycobacterium tuberculosis
Administration:Subcutaneous injection; single dose
Result:Showed the expected signs of experimental autoimmune encephalomyelitis (EAE), which started with tail loss of tonus and continued in an ascending fashion in mice immunized with MOG35-55.
Animal Model:C57BL/6 mice (8-12 weeks)
Dosage:200 μg
Administration:Subcutaneous injection; single dose; analyzed at pre-onset (day 7 post immunization), onset (day 9-13 post immunization) and peak (day 17-19 post immunization)
Result:Increased eosinophil abundance in the spinal cord increases in the course of EAE.
体外研究：
The expanded CD4+ T?cells are largely specific for the myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide 35-55 (MOG35-55), while clonally expanded CD8+ T?cells were non-responsive to myelin peptides or proteins.
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