产品
编 号:F621129
分子式:C38H35Cl2NO7
分子量:688.59
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1mg
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5mg
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生物活性:
HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity. HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. Ex: 530 nm; Em 557 nm.

体外研究:
HKOCl-4 (10 μM) shows an increasing florescence intensity with increasing concentration of hypochlorous acid.HKOCl-4 exhibits a ultra-fast response towards 1 equiv of HOCl (reached a plateau within 2 min) , and it shows a >20-fold increase in fluorescence intensity over other analytes (1 equiv ofOH and ONOOas well as 10 equiv of O2, NO, 1O2, ROO , TBHP and H2O2).HKOCl-4 is first tested and it was proven to be non-toxic in living cells even at a concentration up to 50 μM in RAW264.7 macrophages.
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