产品
编 号:F621088
分子式:C16H16F3N3O5S
分子量:419.38
产品类型
结构图
CAS No: 2055015-61-5
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产品详情
生物活性:
GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM.
体外研究:
GLPG2451 has an EC50 value of 675 nM and an efficacy level of 147% of that of VX770 in G551D/F508del cells.