产品
编 号：F621008
分子式：C25H23BO4
分子量：398.26
分子式：C25H23BO4
分子量：398.26
产品类型
规格
价格
是否有货
结构图
CAS No: 2077980-80-2
产品详情
生物活性：
GLL398, an orally active selective estrogen receptor degrader (SERD), competitively binds to the estrogen receptor with an IC50 value of 1.14 nM. GLL398 exhibits a strong dose-dependent binding profile for the ER with a Y537S point mutation (IC50= 29.5 nM). GLL398 blocks tumor growth in xenograft breast cancer models.
体外研究：
GLL398 is a boron-modified GW5638 analog.
GLL398, an orally active selective estrogen receptor degrader (SERD), competitively binds to the estrogen receptor with an IC50 value of 1.14 nM. GLL398 exhibits a strong dose-dependent binding profile for the ER with a Y537S point mutation (IC50= 29.5 nM). GLL398 blocks tumor growth in xenograft breast cancer models.
体外研究：
GLL398 is a boron-modified GW5638 analog.
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