产品
编 号:F621004
分子式:C19H21NO4S
分子量:359.44
产品类型
结构图
CAS No: 2080311-92-6
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产品详情
生物活性:
ML233 is a non-peptide based potent apelin receptor (APJ) agonist (EC50=3.7 μM). ML233 displays >21-fold selective over the closely related angiotensin 1 (AT1) receptor (>79 μM).
体外研究:
ML233 shows potentially significant binding against several other receptors, including the 5-HT1A, α2C adrenergic, and benzylpiperazine receptors and norepinephrine transporter. ML233 shows some toxicity (LC50=25.8 μM) toward human hepatocyctes.