产品
编 号：F620721
分子式：C19H17F2N3O3
分子量：373.35
分子式：C19H17F2N3O3
分子量：373.35
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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结构图
CAS No: 2133017-36-2
产品详情
生物活性：
GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM.GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. GLP-26 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体外研究：
GLP-26 (0.7-1.7 μM；3 天) 减少转染野生型 HBV 的 HepNTCP-DL 细胞中分泌的 HBeAg，EC50 值为 0.7 μM。
GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM.GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. GLP-26 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体外研究：
GLP-26 (0.7-1.7 μM；3 天) 减少转染野生型 HBV 的 HepNTCP-DL 细胞中分泌的 HBeAg，EC50 值为 0.7 μM。
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