产品
编 号：F620701
分子式：C28H32N6O3
分子量：500.59
分子式：C28H32N6O3
分子量：500.59
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
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询价
结构图
CAS No: 2136270-20-5
产品详情
生物活性：
SPOP-IN-6b is a speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM (patent CN 107141287, SPOP-B-88).
体内研究：
SPOP-IN-6b (40-80 mg/kg; i.p.; daily; for 25 days) can slow down the growth of tumour by suppressing SPOP.Animal Model:Nude mice
Dosage:40 mg/kg, 60 mg/kg, 80 mg/kg
Administration:Intraperitoneal injection; daily; for 25 days
Result:Slowed down the growth of tumour by suppressing SPOP.
体外研究：
SPOP-IN-6b shows IC50s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells.SPOP-IN-6b (0.1-3.0 μM; 10 hours) can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content.
SPOP-IN-6b is a speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM (patent CN 107141287, SPOP-B-88).
体内研究：
SPOP-IN-6b (40-80 mg/kg; i.p.; daily; for 25 days) can slow down the growth of tumour by suppressing SPOP.Animal Model:Nude mice
Dosage:40 mg/kg, 60 mg/kg, 80 mg/kg
Administration:Intraperitoneal injection; daily; for 25 days
Result:Slowed down the growth of tumour by suppressing SPOP.
体外研究：
SPOP-IN-6b shows IC50s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells.SPOP-IN-6b (0.1-3.0 μM; 10 hours) can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content.
产品资料
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