产品
编 号:F620489
分子式:C39H32ClF10N7O5S2
分子量:968.28
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
Lenacapavir (GS-6207) is a HIV-1 capsid inhibitor. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells. Lenacapavir displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells (PBMCs). Lenacapavir is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

体外研究:
Lenacapavir (GS-6207) 是一种有效的衣壳靶向 HIV 复制抑制剂。Lenacapavir 在靶细胞 (EC50=23 pM)、全周期测定 (EC50=25 pM) 和生产细胞 (EC 50=439 下午)。Lenacapavir 会干扰 HIV-1 复制的早期和晚期阶段,但对早期阶段表现出更强的效力。
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