产品
编 号:F620466
分子式:C25H30N4O2
分子量:418.53
产品类型
结构图
CAS No: 2205032-89-7
联系客服
产品详情
生物活性:
ML-211 is a carbamate-based dual inhibitor of acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) (IC50=17 nM) and LYPLA2 (IC50=30 nM). ML-211 also inhibits theserine hydrolase ABHD11 with an IC50 value of 10 nM but is ≥ 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases.