产品
编 号：F619052
分子式：C22H23ClN6O
分子量：422.91
分子式：C22H23ClN6O
分子量：422.91
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
结构图
CAS No: 2231747-18-3
产品详情
生物活性：
N-piperidine Ibrutinib hydrochloride (Compound 1) is a reversible Ibrutinib derivative. N-piperidine Ibrutinib hydrochloride is a potent BTK inhibitor with IC50s of 51.0 and 30.7 nM for WT BTK and C481S BTK, respectively. N-piperidine Ibrutinib hydrochloride can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620 (HY-133137). SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.
体外研究：
N-piperidine Ibrutinib hydrochloride 可作为 BTK 配体用于一系列 PROTAC 的合成。SJF638、SJF678 和 SJF608 是有效的 PROTAC BTK 降解剂，DC50 分别为 374、162 和 8.3 nM。
N-piperidine Ibrutinib hydrochloride (Compound 1) is a reversible Ibrutinib derivative. N-piperidine Ibrutinib hydrochloride is a potent BTK inhibitor with IC50s of 51.0 and 30.7 nM for WT BTK and C481S BTK, respectively. N-piperidine Ibrutinib hydrochloride can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620 (HY-133137). SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.
体外研究：
N-piperidine Ibrutinib hydrochloride 可作为 BTK 配体用于一系列 PROTAC 的合成。SJF638、SJF678 和 SJF608 是有效的 PROTAC BTK 降解剂，DC50 分别为 374、162 和 8.3 nM。
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备