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编 号:F618993
分子式:C18H16Cl2N4O2
分子量:391.25
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生物活性:
FTO-IN-1 is a fat mass and obesity-associated enzyme (FTO) inhibitor extracted from patent WO2018157843A1, compound 32, with an IC50 of <1 μM. FTO-IN-1 can be used for the research of cancer.

体外研究:
FTO-IN-1 (50 μM) inhibits FTO enzyme activity by 62% in vitro.FTO-IN-1 (50 μM) inhibits the viability of SCLC-21H, RH30 and KP3 cells, with IC50s of 2.1 μM, 5.3 μM, and 5.6 μM, respectively.
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