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编 号:F618864
分子式:C59H67F2N7O11S
分子量:1120.27
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CAS No: 2254609-27-1
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SJFα is a 13-atom linker PROTAC based on von Hippel-Lindau ligand. SJFα degrades p38α with a DC50 of 7.16??nM, but is far less effective at degrading p38δ (DC50=299?nM) and does not degrade the other p38 isoforms (β and γ) at concentrations up to 2.5?μM.