产品
编 号：F618760
分子式：C111H211N59O26S
分子量：2820.33
分子式：C111H211N59O26S
分子量：2820.33
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CAS No: 2305815-72-7
产品详情
生物活性：
R8-T198wt is a cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase.
体外研究：
R8-T198wt peptide (KD=323 nM) shows significant affinity for Pim-1. R8-T198wt peptide inhibits p27Kip1 phosphorylation by Pim-1 in cells.R8-T198wt peptide induces G1 arrest and apoptosis in DU145 cells.R8-T198wt treatment also enhances the HA-p27Kip1 expression level.
R8-T198wt is a cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase.
体外研究：
R8-T198wt peptide (KD=323 nM) shows significant affinity for Pim-1. R8-T198wt peptide inhibits p27Kip1 phosphorylation by Pim-1 in cells.R8-T198wt peptide induces G1 arrest and apoptosis in DU145 cells.R8-T198wt treatment also enhances the HA-p27Kip1 expression level.
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