产品
编 号:F066026
分子式:C19H17Cl2N3O3
分子量:406.26
产品类型
结构图
CAS No: 119446-68-3
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产品详情
生物活性:
Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth.
体内研究:
Difenoconazole (0.25-2 mg/L; 暴露 96 h) 会导致斑马鱼胚胎发育中的一系列症状,包括发育抑制、心率减慢、生长退化和形态畸形。Animal Model:Zebrafish
Dosage:0.25, 0.5, 1, 1.5 and 2 mg/L
Administration:Exposure for 96 h
Result:Caused significant body color blackening and decrease in the heart rate of zebrafish larvae over 24 h at 0.5 mg/L.Inhibited the growth weight of adult zebrafish measured after 14 days' exposure at 0.25 mg/L.
体外研究:
Difenoconazole 抑制禾谷镰刀菌 (Fusarium graminearum) 生长,EC50 为 1.69 ~ 19.6 mg/L。Difenoconazole 抑制加链格孢 (Alternaria solani)、茄子叶霉病菌 (Fulvia fulva)、贵腐霉菌 (Botrytis cinerea)、立枯丝核菌 (Rhizoctonia solani) 的生长,EC50s 分别为 0.131、0.069、0.297 和 0.252 mg/L。