产品
编 号:F618475
分子式:C53H67F3N6O8S
分子量:1005.19
产品类型
结构图
CAS No: 2361114-15-8
联系客服
产品详情
生物活性:
PROTAC ER Degrader-4 is a von Hippel-Lindau-based PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM.
体外研究:
PROTAC ER Degrader-4 shows equal to 100% ER degradation at 0.3 μM in the MCF-7 ER degradation cellular assay.