产品
编 号:F618468
分子式:C47H56N10O11
分子量:937.01
产品类型
结构图
CAS No: 2361493-16-3
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产品详情
生物活性:
BSJ-03-123 is a PROTAC connected by ligands for Cereblon and CDK as a potent and novel CDK6-selective small-molecule degrader.
体外研究:
BSJ-03-123 (BSJ) causes a pronounced anti-proliferative effect in CDK6-dependent AML cell lines by inducing a G1 cell-cycle arrest without a measurable increase in apoptosis.