产品
编 号:F618439
分子式:C58H63Cl2N11O10
分子量:1145.09
产品类型
结构图
CAS No: 2369022-68-2
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生物活性:
PROTAC PARP1 degrader is a PARP1 degrader based on MDM2 E3 ligand. It induces significant PARP1 cleavage and programmed cell death. PROTAC PARP1 degrader at 10 μM at 24 h inhibits MDA-MB-231 cell line with an IC50 of 6.12 μM.