产品
编 号:F618406
分子式:C49H58FN9O7S
分子量:936.1
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
结构图
联系客服
产品详情
生物活性:
ACBI1 is a potent and cooperative SMARCA2, SMARCA4 and PBRM1 degrader with DC50s of 6, 11 and 32 nM, respectively. ACBI1 is a PROTAC degrader. ACBI1 shows anti-proliferative activity. ACBI1 induces apoptosis.

体外研究:
ACBI1 (1-10000 nM; 3-7 days) shows anti-proliferative activity.ACBI1 (0.3 μM; 100 h) induces apoptosis in SK-MEL-5 cells.ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase von Hippel-Lindau.
产品资料